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Irma M Sainz Selected Research

High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)

9/2007Kininostatin associates with membrane rafts and inhibits alpha(v)beta3 integrin activation in human umbilical vein endothelial cells.
11/2005[High molecular weight kininogen in inflammation and angiogenesis: a review of its properties and therapeutic applications].
8/2005Modulation of inflammation by kininogen deficiency in a rat model of inflammatory arthritis.
10/2004Inhibition of tumor angiogenesis in vivo by a monoclonal antibody targeted to domain 5 of high molecular weight kininogen.
9/2004A monoclonal antibody to high-molecular weight kininogen is therapeutic in a rodent model of reactive arthritis.

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Irma M Sainz Research Topics

Disease

5Arthritis (Polyarthritis)
02/2008 - 01/2005
5Inflammation (Inflammations)
05/2007 - 09/2004
4Neoplasms (Cancer)
02/2008 - 10/2004
2Carcinoma (Carcinomatosis)
02/2012 - 10/2004
2Rheumatoid Arthritis
05/2007 - 01/2005
1Small Cell Carcinoma
02/2012
1Adenocarcinoma of Lung
02/2012
1Myocardial Infarction
04/2009
1ST Elevation Myocardial Infarction
04/2009
1Thrombosis (Thrombus)
06/2007
1Granuloma
05/2007
1Multiple Myeloma
07/2006
1Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
11/2005
1Enterocolitis
11/2005
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2005
1Psoriasis (Pustulosis Palmaris et Plantaris)
01/2005
1Reactive Arthritis (Reiter Disease)
09/2004

Drug/Important Bio-Agent (IBA)

5High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)IBA
09/2007 - 09/2004
5Monoclonal AntibodiesIBA
07/2006 - 09/2004
4Kininogens (Kininogen)IBA
06/2007 - 01/2005
3Plasma KallikreinIBA
11/2005 - 09/2004
2Peptides (Polypeptides)IBA
06/2007 - 05/2007
2Peptidoglycan (Murein)IBA
05/2007 - 08/2005
2Polysaccharides (Glycans)IBA
05/2007 - 08/2005
2Blood Proteins (Serum Proteins)IBA
11/2005 - 10/2004
1Thyroid Nuclear Factor 1IBA
02/2012
1Plasminogen Activator Inhibitor 1IBA
04/2009
1Plasminogen Activators (Plasminogen Activator)IBA
04/2009
1src-Family KinasesIBA
02/2008
1FibrinIBA
06/2007
1ThrombinFDA Link
06/2007
1Connective Tissue Growth FactorIBA
05/2007
1Thrombospondin 1IBA
05/2007
1benzoyl-prolyl-phenylalanyl-boroarginineIBA
11/2005
1Biomarkers (Surrogate Marker)IBA
01/2005
1HLA Antigens (Human Leukocyte Antigens)IBA
01/2005
1HLA-B27 Antigen (HLA B27 Antigen)IBA
01/2005
1Immunoglobulin G (IgG)IBA
10/2004
1KininsIBA
09/2004

Therapy/Procedure

2Therapeutics
02/2012 - 11/2005
1Intraperitoneal Injections
08/2005